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ATPγS tetralithium salt

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ATPγS tetralithium salt

Catalog No. T22592Cas No. 93839-89-5

ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions.

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Pack Size	Price	Availability
1 mg	$148	In Stock
5 mg	$372	In Stock
10 mg	$570	In Stock
25 mg	$1,052	In Stock
50 mg	$1,710	In Stock
100 mg	$2,860	In Stock

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Product Introduction

Bioactivity

Description	ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions.
In vitro	Enhancing intrinsic fluorescence and inducing aggregation, ATPγS tetralithium salt increases the activity of spinach Rubisco activase[1]. Attenuating inflammatory response with decreased accumulation of cells (48%, P < 0.01) and proteins (57%, P < 0.01) in bronchoalveolar lavage, ATPγS tetralithium salt (50-100 μM final blood concentration) also reduces neutrophil infiltration and extravasation of Evans blue albumin dye into lung tissue[3].
In vivo	Demonstrating preserved lung parenchymal architecture (50 μM final, intravenous), ATPγS tetralithium salt exhibits a dose-dependent effect on Evans blue albumin (EBA) extravasation in LPS-treated mice[3].
Alias	ATP-gamma-S tetralithium salt

Chemical Properties

Molecular Weight	546.98
Formula	C10H12Li4N5O12P3S
Cas No.	93839-89-5

Storage & Solubility Information

Storage

store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 100 mg/mL (182.82 mM)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8282 mL	9.1411 mL	18.2822 mL	91.4110 mL
5 mM	0.3656 mL	1.8282 mL	3.6564 mL	18.2822 mL
10 mM	0.1828 mL	0.9141 mL	1.8282 mL	9.1411 mL
20 mM	0.0914 mL	0.4571 mL	0.9141 mL	4.5706 mL
50 mM	0.0366 mL	0.1828 mL	0.3656 mL	1.8282 mL
100 mM	0.0183 mL	0.0914 mL	0.1828 mL	0.9141 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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